Career

I joined UEA as a joint lecturer in the School of Computing Sciences and the School of Biological Sciences in 1999 after spending postdoctoral years in two of the world’s leading groups in computational biomolecular research.  I spent four years in the group of Professor Nobuhiro Go at the Department of Chemistry, University of Kyoto, Japan, and a further four years in the group of Professor Herman Berendsen at the Department of Chemistry, University of Groningen, The Netherlands.  These postdoctoral positions were funded by personal fellowships: a Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowship, a European Commission Science and Technology Programme Fellowship for Japan, and a European Commission's Biotechnology Programme Fellowship. 

 

My topic of research is protein structure, protein dynamics and protein function and we employ a variety of computational techniques, including simulation methods and bioinformatics.  A particular focus of my research is on protein domain movements and our DynDom webserver (www.cmp.uea.ac.uk/dyndom) is the world’s foremost site for the analysis of protein domain movements.

 

I collaborate with colleagues in Japan and was awarded a JSPS Bridge Fellowship in 2015, a JSPS London Furusato Award in 2009, a JSPS Invitation Fellowship for Research in Japan (Short Term) in 2007, and a Royal Society Outgoing Short Visit grant to visit colleagues in Japan, particularly my long-term collaborator Professor Akio Kitao at the Institute of Molecular and Cellular Biosciences, University of Tokyo.

 

At the School of Computing Sciences, I work with Dr Stephen Laycock on the development of haptic (force-feedback)-based tools for the study of biomolecular interactions (www.haptimol.com) and with Dr Gavin Cawley using machine learning techniques for the study of protein domain movements.

Academic Background

I have a BSc(Hons) in Physics from the University of Bristol and a Diplom in Physics (6-year undergraduate degree) from Johannes-Gutenberg University, Mainz, Germany. I did a PhD on Protein Secondary Structure Prediction at the Department of Molecular Biology at the University of Edinburgh, Scotland, before embarking on my research career.

View graph of relations

ID: 114880