Key Research Interests and Expertise

My research expertise is in micronutrients, in particular iron bioavailability and requirements for optimal health, using a combination of cell/in vitro models and human studies and working in collaboration with colleagues both nationally and internationally.  

Recent publications 

  1. Grootswagers P, Mensink M, Berendsen AAM, Deen CPJ, Kema IP, Bakker SJL, Santoro A, Franceschi C, Meunier N, Brugère CM, Bialecka-Debek A, Rolf K, Fairweather-Tait S, Jennings A, Feskens EJM, de Groot LCPGM. Vitamin B-6 intake is related to physical performance in European older adults - the NU-AGE study. Am J Clin Nutr (accepted).
  2. Montiel-Rojas D, Nilsson A, Santoro A, Bazzocchi A, de Groot LCPGM, Feskens EJM, Berendsen AAM, Madej D, Kaluza J, Pietruszka B, Jennings A, Fairweather-Tait S, Battista G, Capri M, Franceschi C, Kadi F. Fighting sarcopenia in ageing European adults: the importance of the amount and source of dietary proteins. Nutrients (accepted).
  3. Montiel-Rojas D, Santoro A, Nilsson A, Franceschi C, Capri M, Bazzocchi A, Battista G, de Groot LCPGM, Feskens EJM, Berendsen AAM, Bialecka-Debek A, Surala O, Pietruszka B, Fairweather-Tait S, Jennings A, Capel F, Kadi F. Beneficial role of replacing dietary saturated fatty acids by polyunsaturated fatty acids in prevention of sarcopenia: findings from the NU-AGE cohort. Nutrients 2020 (in press).
  4. Malavolti M, Fairweather-Tait SJ, Malagoli C, Vescovi L, Vinceti M, Filippini T.  Lead exposure in an Italian population: food content, dietary intake and risk assessment. Food Research International (in press).  
  5. Ghosh TS, Rampelli S, Jeffery IB, Santoro A, Neto MC, Capri M, Giampieri E, Jennings A, Candela M, Turroni S, Zoetendal E, Hermes GDA, Elodie C, Meunier N, Brugère CM, Pujos-Guillot E, Berendsen AM, de Groot LCPGM, Feskens EJM, Bielak MJ, Kaluza J, Pietruszka B, Comte B, Maijo-Ferre M, Nicoletti C, de Vos W, Fairweather-Tait S, Cassidy A, Brigidi P, Franceschi C, O’Toole PW. Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across 5 European countries. Gut. 2020 Feb 17:gutjnl-2019-319654.
  6. Jongstra R, Mwangi MN, Burgos G, Zeder C, Low JW, Mzembe G, Liria R, Penny M, Andrade MI, Fairweather-Tait S, Felde TZ, Campos H, Phir KS, Zimmermann MB, Wegmüller R. Iron absorption from iron-biofortified sweet potato is higher than regular sweet potato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women. J Nutr, nxaa267, https://doi.org/10.1093/jn/nxaa267.
  7. Parmanand B, Watson M, Boland KJ, Ramamurthy N, Wharton V, Morovat A, Lund EK, Collier J, Le Gall G, Kellingray L, Fairweather-Tait S, Cobbold JF, Narbad A, Ryan JD, Systemic iron reduction by venesection alters the gut microbiome in patients with haemochromatosis, JHEP Reports (2020), doi: https://doi.org/10.1016/j.jhepr.2020.100154.
  8. Montiel-Rojas D, Nilsson A, Santoro A, Franceschi C, Bazzocchi A, Battista G, de Groot LCPGM, Feskens EJM, Berendsen A, Pietruszka B, Januszko O, Fairweather-Tait S, Jennings A, Nicoletti C, Kadi F. Dietary fibre may mitigate sarcopenia risk: findings from the NU-AGE cohort of older European adults. Nutrients 2020, 12, 1075.
  9. Filippini T, Malavolti M, Borrelli F, Izzo AA, Fairweather-Tait SJ, Norneber M, Vinceti M. Green tea (Camelia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews 2020, issue 3, Art No CD005004.
  10. Fairweather-Tait SJ. Reminiscences of my life as a nutritionist - and looking to the future. Eur J Clin Nutr (2020). https://doi.org/10.1038/s41430-020-0573-z.
  11. Filippini T, Malavolti M, Borrelli F, Izzo AA, Fairweather-Tait SJ, Norneber M, Vinceti M. Green tea (Camelia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews 2020, issue 3, Art No CD005004.
  12. Ghosh TS, Rampelli S, Jeffery IB, Santoro A, Neto MC, Capri M, Giampieri E, Jennings A, Candela M, Turroni S, Zoetendal E, Hermes GDA, Elodie C, Meunier N, Brugère CM, Pujos-Guillot E, Berendsen AM, de Groot LCPGM, Feskens EJM, Bielak MJ, Kaluza J, Pietruszka B, Comte B, Maijo-Ferre M, Nicoletti C,14, de Vos W, Fairweather-Tait S, Cassidy A, Brigidi P, Franceschi C, O’Toole PW. Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across 5 European countries. Gut 2020 (in press).
  13. Fairweather-Tait S, Speich C, Mitchikpè CES, Dainty JR. Dietary iron bioavailability: a simple model that can be used to derive country-specific values for adult men and women. Food Nutr Bull. 2019 Nov 20:379572119885482. doi: 10.1177/0379572119885482.].
  14. Jennings A, Tang J, Gillings R, Perfecto A, Dutton J, Speakman J, Fraser WD, Nicoletti C, Berendsen AAM, de Groot LCPGM, Pietruszka B, Jeruszka-Bielak M, Caumon E, Caille A, Ostan R, Franceschi C, Santoro A, Fairweather-Tait SJ. Changing from a Western to a Mediterranean-style diet does not affect iron or selenium status: results of the NU-AGE one year randomized clinical trial in elderly Europeans. Am J Clin Nutr 2020 Jan; 111(1): 98–109.
  15. Johnston BC, Zeraatkar D, Han MA, Vernooij RWM, Valli C, Dib RE, Marshall C, Stover PJ, Fairweather-Tait S, Wojcik G, Bhatia F, de Souza R, Brotons C, Meerpohl JJ, Patel CJ, Djulbegovic B, Alonso-Coello P, Bala MM, Guyatt GH. Unprocessed red meat and processed meat consumption: dietary guideline recommendations. Annals of Internal Medicine 1st October 2019 doi:10.7326/M19-1621.
  16. Rodriguez-Ramiro I, Dell'Aquila C, Ward JL, Neal AL, Bruggraber SFA, Shewry PR, Fairweather-Tait S. Estimation of the iron bioavailability in green vegetables using an in vitro digestion/Caco-2 cell model. Food Chemistry 301, 15 December 2019, 125292https://doi.org/10.1016/j.foodchem.2019.125292.
  17. Jennings A, Berendsen AM, de Groot LCPGM, Feskens EJM, Brzozowska A,   Sicinska E, Pietruszka B, Meunier N, Caumon E, Malpuech-Brugère C, Santoro  A, Ostan R, Franceschi C, Gillings R, O' Neill CM, Fairweather-Tait SJ, Minihane AM, Cassidy A. Mediterranean-style diet improves systolic blood pressure and arterial stiffness in older adults. Hypertension. 2019 Jan 14: HYPERTENSIONAHA11812259. doi: 10.1161/HYPERTENSIONAHA.118.12259.  [Epub ahead of print].
  18. Giampieri E, Ostan R, Guidarelli G, Salvioli S,Berendsen AAM, Brzozowska A, Pietruszka B, Jennings A, Meunier N, Caumon E, Fairweather-Tait S, Sicinska E, Feskens EJM, de Groot LCPGM, Franceschi C, Santoro S. A novel approach to improve the estimation of a diet adherence considering seasonality and short term variability – the NU-AGE Mediterranean diet experience. Front. Physiol. 10:149. doi: 10.3389/fphys.2019.00149.
  19. Parmanand BA, Kellingray L, Le Gall G, Basit AW, Fairweather-Tait S, Narbad A.  A decrease in iron availability to human gut microbiome reduces the growth of potentially pathogenic gut bacteria; an in vitro colonic fermentation study. J Nutritional Biochem 2019;67:20-7. https://doi.org/10.1016/j.jnutbio.2019.01.010.
  20. Santoro A, Guidarelli G, Ostan R, Giampieri E, Fabbri C, Bertarelli C, Nicoletti C, Kadi F, de Groot LCPGM, Feskens E, Berendsen A, Brzozowska A, Januszko O, Kozlowska K, Fairweather-Tait S, Jennings A, Meunier N, Caumon E, Napoli A, Mercatelli D, Battista G, Capri M, Franceschi C, Bazzocchi A. Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study. Eur Radiol. 2019 Feb 4. doi: 10.1007/s00330-018-5973-2. [Epub ahead of print].
  21. Ostan R, Guidarelli G, Giampieri E, Lanzarini C, Berendsen AAM, Januszko O,   Jennings A, Lyon N, Caumon E, Gillings R, Sicinska E, Meunier N, Feskens E,  Pietruszka B, De Groot LCPGM, Fairweather-Tait S, Capri M, Franceschi C,  Santoro A. Cross-sectional analysis of the correlation between daily nutrient intake assessed by 7-day food records and biomarkers of dietary intake among participants of the NU-AGE study. Frontiers in Physiology 2018;9:1359. doi:10.3389/fphys.2018.01359.
  22. Rojas DM, Nilsson A, Ponsot E, Brummer RJ, Fairweather-Tait S, Jennings A, de Groot LC, Berendsen A, Pietruszka B, Madej D, Caumon E, Meunier N, Malpuech-Brugère C, Guidarelli G, Santoro A, Franceschi C, Kadi F. Short telomere length is related to limitations in physical function in elderly European adults. Frontiers in Physiology 2018; 9:1110. doi: 10.3389/fphys.2018.01110.
  23. Maijo M, Ivory K, Clements SJ, Dainty JR, Jennings A, Gillings R, Fairweather-Tait S, Gulisano M, Santoro A, Franceschi C, Carding SR, Nicoletti C.One-year consumption of a Mediterranean-like dietary pattern with vitamin D3  supplements induced small scale but extensive changes of immune cell phenotype, co-receptor expression and innate immune responses in healthy elderly subjects: results from the United Kingdom arm of the NU-AGE trial. Frontiers in Physiology 2018;9:997. doi: 10.3389/fphys.2018.00997.
  24. Fairweather-Tait SJ, de Sesmaisons A. Approaches used to estimate   bioavailability when deriving dietary reference values for iron and zinc in adults. Proc Nutr Soc. 2018 Jul 27:1-7. doi: 10.1017/S0029665118000484.
  25. Jennings A, Cashman KD, Gillings R, Cassidy A, Tang J, Fraser W, Dowling KG, Hull GLJ, Berendsen AAM, de Groot LCPGM, Pietruszka B, Wierzbicka E, Ostan R, Bazzocchi A, Battista G,  Caumon E, Meunier N, Malpuech-Brugère C, Franceschi C, Santoro A, Fairweather-Tait SJ. A Mediterranean-like dietary pattern with vitamin D3 (10 µg/day) supplements reduced rate of bone loss in older Europeans with osteoporosis at baseline: results of a one year randomised controlled trial. Am J Clin Nutr. 2018 Jul 11. doi: 10.1093/ajcn/nqy122. [Epub ahead of print] PMID: 30007343.
  26. Perfecto A, Rodriguez-Ramiro I, Rodriguez-Celma J, Sharp P, Balk J, Fairweather-Tait S. Pea ferritin stability under gastric pH conditions determines the mechanism of iron uptake in Caco-2 cells. J Nutr. 2018 Jun 22. doi: 10.1093/jn/nxy096. [Epub ahead of print] PMID: 29939292.
  27. Chiocchetti GM, De Nadai Fernandes EA, Wawer AA, Fairweather-Tait S, Christides T. In vitro iron bioavailability of Brazilian food-based by-products. Medicines 2018, 5, 45; doi:10.3390/medicines5020045.
  28. Wawer AA, Jennings A, Fairweather-Tait SJ. Iron status in the elderly: A review of recent evidence. Mech Ageing Dev. 2018 Oct;175:55-73. doi:  10.1016/j.mad.2018.07.003.
  29. Moore KL, Rodríguez-Ramiro I, Jones ER, Jones EJ, Rodríguez-Celma J, Halsey K, Domoney C, Shewry PR, Fairweather-Tait S, Balk J. The stage of seed development influences iron bioavailability in pea (Pisum sativum L.). Sci Rep. 2018 May 2;8(1):6865. doi: 10.1038/s41598-018-25130-3.
  30. Lynch S, Pfeiffer CM, Georgieff MK, Brittenham G, Fairweather-Tait S, Hurrell RF, McArdle HJ, Raiten DJ. Biomarkers of nutrition for development (BOND) – iron review. J Nutr. 2018 Jun 1;148(suppl_1):1001S-1067S. doi: 10.1093/jn/nxx036. PMID: 29878148.
  31. Marseglia A, Xu W, Fratiglioni L, Fabbri C, Berendsen AAM, Bialecka-Debek A, Jennings A, Gillings R, Meunier N, Caumon E, Fairweather-Tait S, Pietruszka B, de Groot LCPGM, Santoro A, Franceschi C. Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial. Frontiers in Physiology 4;9:349. doi: 10.3389/fphys.2018.00349. eCollection 2018.

ID: 100381