Biography

After gaining a 1st class (hon) MChem degree from the University of Leeds, U.K. (2006-2010), Rianne continued her studies at Leeds and gained a PhD in “Synthesis of novel functionalised β-ketoiminate and β-diketonate metal complexes for their use in anti-cancer treatment” (2010-2014) under the supervision of Professor Patrick McGowan. She then spent just over a year as a postdoctoral research associate at the University of Edinburgh, U.K., working with Professor Polly Arnold on the synthesis of low-valent uranium complexes supported by macrocyclic “Pacman” type ligands, and studied their abilities to activate small molecules. In August 2016, Rianne was awarded he first independent lectureship at the University of Bradford, where she delivered lectures and research projects in bioinorganic chemistry.

In both 2018 and 2019, Rianne was awarded an August-Wilhelm Scheer visitng professorship at the Technical University of Munch (TUM), where she worked with Professor Fritz Kühn on the synthesis of vanadium N-heteocyclic complexes for applications in catalysis and as potential anticancer compounds. Since August 2019, Rianne has been employed as Lecturer of Inorganic Chemistry at UEA, and more recently she was awarded a prestigious UKRI Future Leaders Fellowship on “Chemical and biological investigations of new vanadium compounds: determining their potential in the treatment of cancer”, which will be conducted between 2021-2025. 

See the groups website for further details.

 

Selected Publications

β‐Diketonate versus β‐Ketoiminate: The Importance of a Ferrocenyl Moiety in Improving the Anticancer Potency M. Allison, D. Wilson, C. M. Pask, P. C. McGowan, R. M. Lord,* ChemBioChem 2020, 21(14), 1988-1996, doi: 10.1002/cbic.202000028

 

Influence of Ligand and Nuclearity on the Cytotoxicity of Cyclometallated C^N^C Platinum(II) Complexes A. Kergreis, R. M. Lord,* S. J. Pike* Chem. Eur. J. 2020, just accepted, doi: 10.1002/chem.202002517

 

Precious metal N-heterocyclic carbene-carbaboranyl complexes: Cytotoxic and selective compounds for the treatment of cancer R. M.Lord,* J. Holmes, F. N. Singer, A. Frith, C. E.Willans, J. Organomet. Chem. 2020, 907, 121062, doi: 10.1016/j.jorganchem.2019.121062

 

β‐Ketoiminato Iridium(III) Organometallic Complexes: Selective Cytotoxicity towards Colorectal Cancer Cells HCT116 p53‐/‐ R. M. Lord,* M. Zegke, I. R. Henderson, C. M. Pask, H. J. Shepherd, Patrick C. McGowan, Chem. Eur. J. 2019, 25(2), 495-500, doi: 10.1002/chem.201804901

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