Biography

 

Paz was born in Madrid (Spain), where she studied Chemistry at the Universidad Autónoma de Madrid until June 1999, when she finished her Master in Chemistry (Organic Chemistry). In July 2001 she obtained her Diploma Thesis at the same University under the supervision of Prof. Antonio M. Echavarren (“Desarrollo de Nuevos Métodos de Formación de  Enlace C-C Catalizados por Pt, Ru y Pd”. Apto), and then carried out her Ph.D. in Chemistry in the same group (October 2004. “Competing Pathways in the Cyclization of 1,6-Enynes Catalyzed by Transition Metals: Selectivity Studies”). On 22nd October 2004, she passed her viva (Summa Cum Laude) and, one week later undertook her new life as a postdoc in Bristol, in the group of Prof. Lloyd-Jones. During her time in Bristol she held the positions of Research Assistant (November 2004) working on “Synthesis of New 3,3'-Binol Derived Substituted Phosphoramidites” for the Ligand Bank (European Community's Sixth Framework Programme); Post-Doctoral Fellow from the Ministerio de Educación y Ciencia (August 2005), working in “Mechanistic and Kinetics Aspects of the Palladium-Catalyzed Cyclization of Dienes and Related Reactions”; and finally Research Associate (August 2007), working on “Development of New Protocols for Alkene Difuntionalisation” financed by the (Engineering and Physical Sciences Research Council (EPSRC), UK). In May 2009, Dr. Muñoz returned to Madrid, Spain with a prestigious Ramón y Cajal Award to work at the Insituto de Química Orgánica General (IQOG-CSIC), where she started her research into the discovery of new platinum-catalysed reactions of allenes. She joined the UEA as Lecturer in Chemistry from September 2011 and was promoted to Senior Lecturer in 2017.


Research interests

Dr Muñoz is an organic chemist with particular interest in the discovery and development of new organic and organometallic reactions, the use of physical-organic-inorganic chemistry knowledge to study the mechanisms involved, in particular using isotopic labelling, kinetics, simulations and NMR techniques, and the application of the knowledge acquire to the synthesis of small organic and organometallic molecules with potential biological activity.

Her current research involves the discovery and development of novel transition metal-catalysed reactions of allenes, including:

  • Platinum- and gold-catalysed addition of nucleophiles to allenes
  • Metal-catalysed reaction of polyallenic systems
  • Synthesis of metal complex with allenic ligands for catalysis and as metallodrugs
  • Mechanistic studies on metal-catalysed reactions of allenes
  • Develpoment of new methodologies involving heterobimetallic catalysis

Selected publications

Allene-derived gold and platinum complexes: synthesis and first application in catalysis

Hanna K. Maliszewska, David L. Hughes and M. Paz Muñoz

Dalton Trans., 202049, 4034-4038.

 

Unraveling mechanistic insights in the plainum-catalysed dihydroalkoxylation of allenes

M. T. Quirós, E. Gómez-Bengoa, M. P. Muñoz

Pure Appl. Chem. 2020, 92(1), 167-177.

Article for a collection of invited papers based on presentations at the 24th IUPAC International Conference on Physical Organic Chemistry (ICPOC 24) held in Faro, Portugal, 1–6 July 2018.

 

Platinum and Gold Catalysis: a la Carte Hydroamination of Terminal Activated Allenes with Azoles.

 J. M. Alonso, M. P. Muñoz*

Org. Lett. 2019, 21 (18), 7639-7644.

 

 J. M. Alonso, M. P. Muñoz*
 ChemCatChem, 201810, 2646.
 

 

"Synthesis of a Novel Type of 2,3'-BIMs via Platinum-Catalysed Reaction of Indolylallenes with Indoles"

L. Cooper, J. M. Alonso, L. Eagling, H. Newson, S. Herath, C. Thomson, A. Lister, C. Howsham, B. Cox,
M. P. Muñoz*

Chem. Eur. J. 2018, 24, 6105.

 

"Twists and Turns of Platinum-Allene Complexes: NMR Techniques for the Study of the Dynamic Behavior in Solution"

M. Teresa Quiroś, MaríaPazMuñoz,* Jeppe Christensen and Simon J.Coles 

Organometallics201736 (2), pp 318–330.

 

 








Career

  • 1994 to 1999 Universidad Autónoma de Madrid, Spain. BSc (Hons) in Organic Chemistry. First Class
  • 1999 to 2001 Universidad Autónoma de Madrid, Spain. MSc in Organic Chemistry.
  • 2001 to 2004 Universidad Autónoma de Madrid, Spain. PhD. Summa Cum Laude.
  • 2004 to 2005 University of Bristol, UK. Research assistant.
  • 2005 to 2007 University of Bristol, UK. Postdoctoral fellow.
  • 2007 to 2009 University of Bristol, UK. Research Associate.
  • 2009 to 2011 Instituto de Química Orgánica General (IQOG) – CSIC, Madrid, Spain. Ramón y Cajal Fellow.
  • 2011 to 2017 University of East Anglia, UK. Lecturer in Organic Chemistry.
  • 2017 to date University of East Anglia, UK. Senior Lecturer in Organic Chemistry.

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