PhD Positions

Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Julie Sanderson obtained her BSc (Hons) in Pharmacology, University of Leeds, 1986 and her PhD in ocular physiology from the School of Biological Sciences, University of East Anglia, 1991. She then held research associate and senior demonstrator positions in the School of Biological Sciences, University of East Anglia, before being appointed to a post as a Lecturer in Pharmacology in the School of Chemical Sciences and Pharmacy, University of East Anglia in 2004.  She is currently a Senior Lecturer in Pharmaceutical Cell Biology in the School of Pharmacy.

Research interests include: ocular cell biology, pharmacology and pathophysiology including purinoceptor signalling in the retina (neural retina and the retinal pigment epithelium), molecular mechanisms underlying visual field loss in glaucoma and mechanisms of cataract formation. A central theme is calcium cell signalling.

Selected Publications

Human organotypic retinal cultures (HORCs) as a chronic experimental model for investigation of retinal ganglion cell degeneration.
Osborne, A., Hopes, M., Wright, P., Broadway, D. C., Sanderson, J.
Experimental Eye Research, 2016, 143, pp. 28-38
DOI:  10.1016/j.exer.2015.09.012

Hydrostatic Pressure does not cause detectable changes to Survival of Human Retinal Ganglion.
Osborne, A., Aldarwesh, A., Rhodes, J. D., Broadway, D. C., Everitt, C., Sanderson.
J.PLoS One, 2015. 10(1): e0115591.
DOI: 10.1371/journal.pone.0115591
DOI: 10.1371/journal.pone.0115591

Purines in the eye : recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork, cornea and lacrimal gland.
Sanderson, J., Dartt, D., Trinkaus-Randall, V., Pintor, J., Civan, M., Delamere, N., Fletcher, E., Salt, T., Grosche, A., Mitchell, C.
Experimental Eye Research, 2014, 127.pp. 270-279.
DOI: 10.1016/j.exer.2014.08.009

P2X7 receptor activation mediates retinal ganglion cell death in a human retina model of ischemic neurodegeneration.
Niyadurupola, N., Sidaway, P., Ma, N., Sanderson, J., Broadway, D., Rhodes, J.
Investigative Ophthalmology & Visual Science, 2013, 54. pp. 2163-2170.
DOI: 10.1167/iovs.12-10968

The development of human organotypic retinal cultures (HORCs) to study retinal neurodegeneration
Niyadurupola N, Sidaway P, Osborne A, Broadway DC, Sanderson J.
Br. J. Ophthalmol. 2011, 95, 720-726.

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