Key Research Interests and Expertise

I am a biomedical scientist with primary interests in the use of human tissue to study human eye disease. In particular, I am interested in wound-healing events that follow cataract surgery, which lead to a secondary visual loss known as posterior capsule opacification (PCO). Through the use of human tissue the laboratory aims to further our understanding of the cell and molecular mechanisms underpinning PCO and identify novel targets for future therapeutic development.

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Current Research Projects

  • Investigation of TGFß signalling involvement in matrix contraction and cell transdifferentiation
  • Gene expression and functional analysis of ocular cells
  • Development of human disease models to serve as pre-clinical evaluation tools
  • Optimise novel drug delivery mechanisms to prevent PCO
  • iPSC-derived lentoid formation

 

Life in our research group

The laboratory employs human ocular cell and tissue culture models as experimental systems to understand the human condition and develop appropriate therapies. The laboratory is equipped with dedicated state-of-the-art analysis tools that facilitate the research programme. There is a good blend of experienced post-doctoral scientists and enthusiastic students eager to learn. The group has international standing within our area of expertise and laboratory members get the opportunity to present their work across the world at meetings in North America, Asia and Europe. This experience is valuable to the development of individuals and the team as a whole.

PhD Positions 

Click here for current PhD opportunities in Biological Sciences. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Postdocs & Fellows

I am always happy to discuss possibilities for post-doctoral work and collaborations and Fellowship schemes with me acting as a sponsor.

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