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Which frail older people are dehydrated? The UK DRIE study

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Which frail older people are dehydrated? The UK DRIE study. / Hooper, Lee; Bunn, Diane; Downing, Alice; Jimoh, Florence; Groves, Joyce; Free, Carol; Cowap, Vicky ; Potter, John; Hunter, Paul; Shepstone, Lee.

In: The Journal of Gerontology: Medical Sciences, Vol. 71, No. 10, 10.2016, p. 1341-1347.

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Hooper, Lee ; Bunn, Diane ; Downing, Alice ; Jimoh, Florence ; Groves, Joyce ; Free, Carol ; Cowap, Vicky ; Potter, John ; Hunter, Paul ; Shepstone, Lee. / Which frail older people are dehydrated? The UK DRIE study. In: The Journal of Gerontology: Medical Sciences. 2016 ; Vol. 71, No. 10. pp. 1341-1347.

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@article{43eef5d15369456e8dd411b15e1a1b00,
title = "Which frail older people are dehydrated? The UK DRIE study",
abstract = "Background: Water-loss dehydration in older people is associated with increased mortality and disability. We aimed to assess the prevalence of dehydration in older people living in UK long-term care, and associated cognitive, functional and health characteristics.  Methods: The Dehydration Recognition In our Elders (DRIE) cohort study included people ≥65 years living in long-term care without heart or renal failure. In a cross-sectional baseline analysis we assessed serum osmolality, previously suggested dehydration risk factors, general health, markers of continence, cognitive and functional health, nutrition status and medications. Univariate linear regression was used to assess relationships between participant characteristics and serum osmolality, then associated characteristics entered into stepwise backwards multivariate linear regression.   Results: DRIE included 188 residents (mean age 86 years, 66{\%} women) of whom 20{\%} were dehydrated (serum osmolality >300mOsm/kg). Linear and logistic regression suggested that renal, cognitive and diabetic status were consistently associated with serum osmolality and odds of dehydration, while potassium-sparing diuretics, sex, number of recent health contacts, and bladder incontinence were sometimes associated. Thirst was not associated with hydration status.  Conclusions: DRIE found high prevalence of dehydration in older people living in UK long-term care, reinforcing the proposed association between cognitive and renal function and hydration. Dehydration is associated with increased mortality and disability in older people, but trials to assess effects of interventions to support healthy fluid intakes in older people living in residential care are needed to enable us to formally assess causal direction and any health benefits of increasing fluid intakes.",
keywords = "Dehy, Aged, Osmolar Concentration, dementia , Diabetes Mellitus, glomerular filtration rate , Residential Facilities, Risk Factors, Long-Term Care",
author = "Lee Hooper and Diane Bunn and Alice Downing and Florence Jimoh and Joyce Groves and Carol Free and Vicky Cowap and John Potter and Paul Hunter and Lee Shepstone",
year = "2016",
month = "10",
doi = "10.1093/gerona/glv205",
language = "English",
volume = "71",
pages = "1341--1347",
journal = "The Journal of Gerontology: Medical Sciences",
number = "10",

}

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TY - JOUR

T1 - Which frail older people are dehydrated? The UK DRIE study

AU - Hooper, Lee

AU - Bunn, Diane

AU - Downing, Alice

AU - Jimoh, Florence

AU - Groves, Joyce

AU - Free, Carol

AU - Cowap, Vicky

AU - Potter, John

AU - Hunter, Paul

AU - Shepstone, Lee

PY - 2016/10

Y1 - 2016/10

N2 - Background: Water-loss dehydration in older people is associated with increased mortality and disability. We aimed to assess the prevalence of dehydration in older people living in UK long-term care, and associated cognitive, functional and health characteristics.  Methods: The Dehydration Recognition In our Elders (DRIE) cohort study included people ≥65 years living in long-term care without heart or renal failure. In a cross-sectional baseline analysis we assessed serum osmolality, previously suggested dehydration risk factors, general health, markers of continence, cognitive and functional health, nutrition status and medications. Univariate linear regression was used to assess relationships between participant characteristics and serum osmolality, then associated characteristics entered into stepwise backwards multivariate linear regression.   Results: DRIE included 188 residents (mean age 86 years, 66% women) of whom 20% were dehydrated (serum osmolality >300mOsm/kg). Linear and logistic regression suggested that renal, cognitive and diabetic status were consistently associated with serum osmolality and odds of dehydration, while potassium-sparing diuretics, sex, number of recent health contacts, and bladder incontinence were sometimes associated. Thirst was not associated with hydration status.  Conclusions: DRIE found high prevalence of dehydration in older people living in UK long-term care, reinforcing the proposed association between cognitive and renal function and hydration. Dehydration is associated with increased mortality and disability in older people, but trials to assess effects of interventions to support healthy fluid intakes in older people living in residential care are needed to enable us to formally assess causal direction and any health benefits of increasing fluid intakes.

AB - Background: Water-loss dehydration in older people is associated with increased mortality and disability. We aimed to assess the prevalence of dehydration in older people living in UK long-term care, and associated cognitive, functional and health characteristics.  Methods: The Dehydration Recognition In our Elders (DRIE) cohort study included people ≥65 years living in long-term care without heart or renal failure. In a cross-sectional baseline analysis we assessed serum osmolality, previously suggested dehydration risk factors, general health, markers of continence, cognitive and functional health, nutrition status and medications. Univariate linear regression was used to assess relationships between participant characteristics and serum osmolality, then associated characteristics entered into stepwise backwards multivariate linear regression.   Results: DRIE included 188 residents (mean age 86 years, 66% women) of whom 20% were dehydrated (serum osmolality >300mOsm/kg). Linear and logistic regression suggested that renal, cognitive and diabetic status were consistently associated with serum osmolality and odds of dehydration, while potassium-sparing diuretics, sex, number of recent health contacts, and bladder incontinence were sometimes associated. Thirst was not associated with hydration status.  Conclusions: DRIE found high prevalence of dehydration in older people living in UK long-term care, reinforcing the proposed association between cognitive and renal function and hydration. Dehydration is associated with increased mortality and disability in older people, but trials to assess effects of interventions to support healthy fluid intakes in older people living in residential care are needed to enable us to formally assess causal direction and any health benefits of increasing fluid intakes.

KW - Dehy

KW - Aged

KW - Osmolar Concentration

KW - dementia

KW - Diabetes Mellitus

KW - glomerular filtration rate

KW - Residential Facilities

KW - Risk Factors

KW - Long-Term Care

U2 - 10.1093/gerona/glv205

DO - 10.1093/gerona/glv205

M3 - Article

VL - 71

SP - 1341

EP - 1347

JO - The Journal of Gerontology: Medical Sciences

T2 - The Journal of Gerontology: Medical Sciences

JF - The Journal of Gerontology: Medical Sciences

IS - 10

ER -

ID: 62760393