HomePublications

The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident

Research output: Contribution to journalArticle

Documents

DOI

Authors

  • Richard Puleston
  • Cathy Mallaghan
  • Deborah Modha
  • Paul Hunter
  • Jonathan Nguyen-Van-Tam
  • Christopher Regan
  • Gordon Nichols
  • Rachel Chalmers

Organisational units

Abstract

We report the first identified outbreak of cryptosporidiosis with ryptosporidium cuniculus following a water quality incident in Northamptonshire, UK. A standardised, enhanced Cryptosporidium exposure questionnaire was administered to all cases of cryptosporidiosis after the incident. Stool
samples, water testing, microscopy slides and rabbit gut contents positive for Cryptosporidium were typed at the Cryptosporidium Reference Unit, Singleton Hospital, Swansea. Twenty-three people were microbiologically linked to the incident although other evidence suggests an excess of 422 cases of cryptosporidiosis above baseline. Most were adult females; unusually for cryptosporidiosis there were no affected children identified under the age of 5 years. Water consumption was possibly higher than in national drinking water consumption patterns. Diarrhoea duration was negatively correlated to distance from the water treatment works where the contamination occurred. Oocyst
counts were highest in water storage facilities. This outbreak is the first caused by C. cuniculus infection to have been noted and it has conclusively demonstrated that this species can be a human pathogen. Although symptomatically similar to cryptosporidiosis from C. parvum or C. hominis, this
outbreak has revealed some differences, in particular no children under 5 were identified and females were over-represented. These dissimilarities are unexplained although we postulate possible explanations.

Details

Original languageEnglish
Pages (from-to)41-50
Number of pages10
JournalJournal of Water and Health
Volume12
Issue number1
DOIs
StatePublished - 2014
Peer-reviewedYes

Keywords

    Research areas

  • Cryptosporidium, outbreak, rabbit, water quality

View graph of relations

ID: 44348345

Related by journal