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Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect

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Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect. / Sales, Kris; Vasudeva, Ramakrishnan; Dickinson, Matthew E.; Godwin, Joanne L.; Lumley, Alyson J.; Michalczyk, Łukasz; Hebberecht, Laura; Thomas, Paul; Franco, Aldina; Gage, Matthew J. G.

In: Nature Communications, Vol. 9, 4771, 13.11.2018.

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Sales, Kris ; Vasudeva, Ramakrishnan ; Dickinson, Matthew E. ; Godwin, Joanne L. ; Lumley, Alyson J. ; Michalczyk, Łukasz ; Hebberecht, Laura ; Thomas, Paul ; Franco, Aldina ; Gage, Matthew J. G. / Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect. In: Nature Communications. 2018 ; Vol. 9.

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@article{00ff8f1fd1a6413bac0942e64a1a056d,
title = "Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect",
abstract = "Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising most of biodiversity and being more influenced by temperature variation. Using a flour beetle model system, we find that heatwave conditions (5 to 7 °C above optimum for 5 days) damaged male, but not female, reproduction. Heatwaves reduce male fertility and sperm competitiveness, and successive heatwaves almost sterilise males. Heatwaves reduce sperm production, viability, and migration through the female. Inseminated sperm in female storage are also damaged by heatwaves. Finally, we discover transgenerational impacts, with reduced reproductive potential and lifespan of offspring when fathered by males, or sperm, that had experienced heatwaves. This male reproductive damage under heatwave conditions provides one potential driver behind biodiversity declines and contractions through global warming.",
keywords = "Animal physiology, Climate-change, Ecology, Evolutionary ecology",
author = "Kris Sales and Ramakrishnan Vasudeva and Dickinson, {Matthew E.} and Godwin, {Joanne L.} and Lumley, {Alyson J.} and {\L}ukasz Michalczyk and Laura Hebberecht and Paul Thomas and Aldina Franco and Gage, {Matthew J. G.}",
year = "2018",
month = nov,
day = "13",
doi = "10.1038/s41467-018-07273-z",
language = "English",
volume = "9",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

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TY - JOUR

T1 - Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect

AU - Sales, Kris

AU - Vasudeva, Ramakrishnan

AU - Dickinson, Matthew E.

AU - Godwin, Joanne L.

AU - Lumley, Alyson J.

AU - Michalczyk, Łukasz

AU - Hebberecht, Laura

AU - Thomas, Paul

AU - Franco, Aldina

AU - Gage, Matthew J. G.

PY - 2018/11/13

Y1 - 2018/11/13

N2 - Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising most of biodiversity and being more influenced by temperature variation. Using a flour beetle model system, we find that heatwave conditions (5 to 7 °C above optimum for 5 days) damaged male, but not female, reproduction. Heatwaves reduce male fertility and sperm competitiveness, and successive heatwaves almost sterilise males. Heatwaves reduce sperm production, viability, and migration through the female. Inseminated sperm in female storage are also damaged by heatwaves. Finally, we discover transgenerational impacts, with reduced reproductive potential and lifespan of offspring when fathered by males, or sperm, that had experienced heatwaves. This male reproductive damage under heatwave conditions provides one potential driver behind biodiversity declines and contractions through global warming.

AB - Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising most of biodiversity and being more influenced by temperature variation. Using a flour beetle model system, we find that heatwave conditions (5 to 7 °C above optimum for 5 days) damaged male, but not female, reproduction. Heatwaves reduce male fertility and sperm competitiveness, and successive heatwaves almost sterilise males. Heatwaves reduce sperm production, viability, and migration through the female. Inseminated sperm in female storage are also damaged by heatwaves. Finally, we discover transgenerational impacts, with reduced reproductive potential and lifespan of offspring when fathered by males, or sperm, that had experienced heatwaves. This male reproductive damage under heatwave conditions provides one potential driver behind biodiversity declines and contractions through global warming.

KW - Animal physiology

KW - Climate-change

KW - Ecology

KW - Evolutionary ecology

U2 - 10.1038/s41467-018-07273-z

DO - 10.1038/s41467-018-07273-z

M3 - Article

VL - 9

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 4771

ER -

ID: 145875891