HomePublications

Are pregnant women who are living with overweight or obesity at greater risk of developing iron deficiency/anaemia?

Research output: Contribution to journalArticle

Open Access permissions

Open

Documents

DOI

Authors

Organisational units

Abstract

Low-grade inflammation is often present in people living with obesity. Inflammation can impact iron uptake and metabolism through elevation of hepcidin levels. Obesity is a major public health issue globally, with pregnant women often affected by the condition. Maternal obesity is associated with increased pregnancy risks including iron deficiency (ID) and iron-deficiency anaemia (IDA)—conditions already highly prevalent in pregnant women and their newborns. This comprehensive review assesses whether the inflammatory state induced by obesity could contribute to an increased incidence of ID/IDA in pregnant women and their children. We discuss the challenges in accurate measurement of iron status in the presence of inflammation, and available iron repletion strategies and their effectiveness in pregnant women living with obesity. We suggest that pre-pregnancy obesity and overweight/obese pregnancies carry a greater risk of ID/IDA for the mother during pregnancy and postpartum period, as well as for the baby. We propose iron status and weight gain during pregnancy should be monitored more closely in women who are living with overweight or obesity.

Details

Original languageEnglish
Article number1572
JournalNutrients
Volume13
Issue number5
Early online date7 May 2021
DOIs
Publication statusPublished - May 2021
Peer-reviewedYes

Keywords

    Research areas

  • pregnancy, anaemia, iron deficiency, overweight, obesity, inflammation

View graph of relations

ID: 187507655