1. Article › Research › Peer-reviewed
  2. Published

    Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform

    Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S. A., George, V., Kalra, S., Kondrashov, A., Hoang, M. D., Mosqueira, D., Patel, A., Prodanov, L., Rajamohan, D., Skarnes, W. C., Smith, J. G. W. & Young, L. E., Jul 2016, In : Biochimica et Biophysica Acta. 1863, 7, p. 1728-1748 21 p.

    Research output: Contribution to journalArticle

  3. Published

    Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture

    Celiz, A. D., Smith, J. G. W., Patel, A. K., Langer, R., Anderson, D. G., Barrett, D. A., Young, L. E., Davies, M. C., Denning, C. & Alexander, M. R., 30 Nov 2014, In : Biomaterials Science. 2, 11, p. 1604-1611 8 p.

    Research output: Contribution to journalArticle

  4. Published

    CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

    Mosqueira, D., Mannhardt, I., Bhagwan, J. R., Lis-Slimak, K., Katili, P., Scott, E., Hassan, M., Prondzynski, M., Harmer, S. C., Tinker, A., Smith, J. G. W., Carrier, L., Williams, P. M., Gaffney, D., Eschenhagen, T., Hansen, A. & Denning, C., 14 Nov 2018, In : European Heart Journal. 39, 43, p. 3879-3892 14 p.

    Research output: Contribution to journalArticle

  5. Published

    Dental Pulp Cell Behavior in Biomimetic Environments

    Smith, J. G., Smith, A. J., Shelton, R. M. & Cooper, P. R., 2015, In : Journal of Dental Research. 94, 11, p. 1552-1559

    Research output: Contribution to journalArticle

  6. Published

    Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation

    Celiz, A. D., Smith, J. G. W., Patel, A. K., Hook, A. L., Rajamohan, D., George, V. T., Flatt, L., Patel, M. J., Epa, V. C., Singh, T., Langer, R., Anderson, D. G., Allen, N. D., Hay, D. C., Winkler, D. A., Barrett, D. A., Davies, M. C., Young, L. E., Denning, C. & Alexander, M. R., 15 Jul 2015, In : Advanced Materials. 27, 27, p. 4006-4012 7 p.

    Research output: Contribution to journalArticle

  7. Published

    Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion

    Hammad, M., Rao, W., Smith, J. G. W., Anderson, D. G., Langer, R., Young, L. E., Barrett, D. A., Davies, M. C., Denning, C. & Alexander, M. R., 28 Jul 2016, In : Biomaterials Science. 4, 9, p. 1381-1391

    Research output: Contribution to journalArticle

  8. Published

    Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics

    Bhagwan, J. R., Mosqueira, D., Chairez-Cantu, K., Mannhardt, I., Bodbin, S. E., Bakar, M., Smith, J. G. W. & Denning, C., Aug 2020, In : Journal of Molecular and Cellular Cardiology. 145, p. 43-53 11 p.

    Research output: Contribution to journalArticle

  9. Published

    Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits

    Smith, J. G. W., Owen, T., Bhagwan, J. R., Mosqueira, D., Scott, E., Mannhardt, I., Patel, A., Barriales-Villa, R., Monserrat, L., Hansen, A., Eschenhagen, T., Harding, S. E., Marston, S. & Denning, C., 13 Nov 2018, In : Stem Cell Reports. 11, 5, p. 1226-1243 18 p.

    Research output: Contribution to journalArticle

  10. Published

    Materials for stem cell factories of the future

    Celiz, A. D., Smith, J. G. W., Langer, R., Anderson, D. G., Winkler, D. A., Barrett, D. A., Davies, M. C., Young, L. E., Denning, C. & Alexander, M. R., 21 May 2014, In : Nature Materials. 13, p. 570-579 10 p.

    Research output: Contribution to journalArticle

  11. Published

    Mitochondrial DNA: Hotspot for potential gene modifiers regulating hypertrophic cardiomyopathy

    Kargaran, P. K., Evans, J. M., Bodbin, S. E., Smith, J. G. W., Nelson, T. J., Denning, C. & Mosqueira, D., 23 Jul 2020, In : Journal of Clinical Medicine. 9, 8

    Research output: Contribution to journalArticle

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