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Chemistry of Life Processes

Organisational unit: Research Group

  1. 2021
  2. E-pub ahead of print

    Frontiers in PROTACs

    Hughes, G. R., Dudey, A. P., Hemmings, A. M. & Chantry, A., 17 Apr 2021, In : Drug Discovery Today.

    Research output: Contribution to journalArticle

  3. Published

    Allosteric site on SHIP2 identified through fluorescent ligand screening and crystallography: a potential new target for intervention

    Whitfield, H., Hemmings, A. M., Mills, S. J., Baker, K., White, G., Rushworth, S., Riley, A. M., Potter, B. V. L. & Brearley, C. A., 8 Apr 2021, In : Journal of Medicinal Chemistry. 64, 7, p. 3813–3826 14 p.

    Research output: Contribution to journalArticle

  4. Published

    Electron transfer from haem to the di-iron ferroxidase centre in bacterioferritin

    Svistunenko, D. A., Pullin, J., Bradley, J., Moore, G., Le Brun, N. & Wilson, MT., 6 Apr 2021, In : Angewandte Chemie International Edition. 60, 15, p. 8376-8379 4 p.

    Research output: Contribution to journalArticle

  5. Published

    Iron oxidation in Escherichia coli bacterioferritin ferroxidase centre, a site designed to react rapidly with H2O2 but slowly with O2

    Pullin, J., Wilson, MT., Clémancey, M., Blondin, G., Bradley, J. M., Moore, G. R., Le Brun, N. E., Lučić, M., Worrall, J. A. R. & Svistunenko, D. A., 6 Apr 2021, In : Angewandte Chemie International Edition. 60, 15, p. 8361-8369 9 p.

    Research output: Contribution to journalArticle

  6. E-pub ahead of print

    DEER and RIDME Measurements of the Nitroxide-Spin Labelled Copper-Bound Amine Oxidase Homodimer from Arthrobacter Globiformis

    Russell, H., Stewart, R., Prior, C., Oganesyan, V. S., Gaule, T. G. & Lovett, J. E., 29 Mar 2021, In : Applied Magnetic Resonance.

    Research output: Contribution to journalArticle

  7. E-pub ahead of print

    The flavodoxin FldA activates the class 1a ribonucleotide reductase of Campylobacter jejuni

    Alqurashi, A., Alfs, L., Swann, J., Butt, J. & Kelly, D. J., 15 Mar 2021, In : Molecular Microbiology.

    Research output: Contribution to journalArticle

  8. Published

    Rhodium(III) dihalido complexes: The effect of ligand substitution and halido coordination on increasing cancer cell potency

    Lord, R. M., Zegke, M., Basri, A. M., Pask, C. M. & McGowan, P. C., 1 Feb 2021, In : Inorganic Chemistry. 60, 3, p. 2076-2086 11 p.

    Research output: Contribution to journalArticle

  9. 2020
  10. Published

    Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced fit structural mechanism

    Acquistapace, I. M., Zietek, M. A., Li, A. W. H., Salmon, M., Kuhn, I., Bedford, M. R., Brearley, C. A. & Hemmings, A. M., 18 Dec 2020, In : The Journal of Biological Chemistry. 295, 51, p. 17724-17737 14 p.

    Research output: Contribution to journalArticle

  11. Published

    The cation diffusion facilitator protein MamM's cytoplasmic domain exhibits metal-type dependent binding modes and discriminates against Mn2+

    Barber-Zucker, S., Hall, J., Froes, A., Kolusheva, S., MacMillan, F. & Zarivach, R., 4 Dec 2020, In : The Journal of Biological Chemistry. 295, 49, p. 16614-16629 16 p.

    Research output: Contribution to journalArticle

  12. Published

    Influence of ligand and nuclearity on the cytotoxicity of cyclometallated C^N^C platinum(II) complexes

    Kergreis, A., Lord, R. M. & Pike, S. J., 20 Nov 2020, In : Chemistry - A European Journal. 26, 65, p. 14938-14946 9 p.

    Research output: Contribution to journalArticle

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