Key Research Interests and Expertise

 The group is interested in three major topics:
• The analysis of components of the extracellular matrix and the their biological functions in vivo
• The biological functions of the prototype member of the annexin protein family, Annexin A5
• The role of perivascular cells during angiogenesis and regenerative processes in skeletal muscle

Current Research Projects
 

• Analysis of the consequences of the deficiency of the major collagen IV isoform α1.α1.α2(IV) in vivo by the use of knockout mouse models
• Roles of annexin A5 deficiency in knockout mouse models on diverse biological processes, like calcification of cartilage and bone, vascular development and apoptosis
• Analysis of the role of annexin A5 in modulating the phagocytosis of apoptotic cells in vivo, the induction of immune reactions and autoimmunity
• In vivo functions of murine pericytes, phenotype analysis and their role in angiogenesis 
• Exploration of the potential capacities of pericytes as stem cells for differentiation to mesenchymal lineages (adipogenic, osteoblastic, chondrogenic) 
• Contributions of pericytes and satellite cells during muscle regeneration in normal tissues and in various muscle diseases


PhD Positions

Click here for current PhD opportunities in Biological Sciences. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

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